SCHEMBL1198511

SCHEMBL1198511

O=c1oc(-c2cc(Br)nn2-c2ncc(Cl)cc2Cl)nc2c(Cl)cc(Cl)cc12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29912889 1.00 MAPT (0.30) MAPT
SCHEMBL15984460 0.92 DHODH (0.33) MAPT
SCHEMBL29791544 0.92 DHODH (0.33) MAPT
SCHEMBL15984458 0.92 — —
SCHEMBL30749778 0.87 DHODH (0.40) MAPT
SCHEMBL950250 0.87 DHODH (0.40) MAPT
SCHEMBL15984456 0.82 APEX1 (0.30) —
SCHEMBL28529761 0.82 DHODH (0.38) —
SCHEMBL15984457 0.81 MAPT (0.44) MAPT
SCHEMBL5503889 0.81 C1R (0.37) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057843-B Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2024-04-30 — — CN disclosed
CN-115057843-A Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2022-09-16 — — CN disclosed
EP-2295425-B1 1-SUBSTITUTED PYRIDYL-PYRAZOLYL AMIDE COMPOUND AND USES THEREOF SHENYANG SCIENCREAT CHEMICALS CO LTD (CN) 2016-09-07 — — EP disclosed
US-8933234-B2 O-amino benzonitrile compounds, method for preparing same and uses thereof HANGZHOU UDRAGON CHEMICAL CO., LTD. (CN) 2015-01-13 — — US disclosed
US-8933234-B2 O-amino benzonitrile compounds, method for preparing same and uses thereof HANGZHOU UDRAGON CHEMICAL CO., LTD. (CN) 2015-01-13 — — US disclosed
US-20140243376-A1 O-AMINO BENZONITRILE COMPOUNDS, METHOD FOR PREPARING SAME AND USES THEREOF HANGZHOU UDRAGON CHEMICAL CO., LTD. (CN) 2014-08-28 — — US disclosed
US-20140243376-A1 O-AMINO BENZONITRILE COMPOUNDS, METHOD FOR PREPARING SAME AND USES THEREOF HANGZHOU UDRAGON CHEMICAL CO., LTD. (CN) 2014-08-28 — — US disclosed
US-8492409-B2 1-substituted pyridyl-pyrazolyl amide compounds and uses thereof SINOCHEM CORPORATION (CN) 2013-07-23 — — US disclosed
US-8492409-B2 1-substituted pyridyl-pyrazolyl amide compounds and uses thereof SINOCHEM CORPORATION (CN) 2013-07-23 — — US disclosed
US-8492409-B2 1-substituted pyridyl-pyrazolyl amide compounds and uses thereof SINOCHEM CORPORATION (CN) 2013-07-23 — — US disclosed
EP-2295425-A1 1-SUBSTITUTED PYRIDYL-PYRAZOLYL AMIDE COMPOUNDS AND USES THEREOF Sinochem Corporation (CN) 2011-03-16 — — EP disclosed
EP-2295425-A1 1-SUBSTITUTED PYRIDYL-PYRAZOLYL AMIDE COMPOUNDS AND USES THEREOF Sinochem Corporation (CN) 2011-03-16 — — EP disclosed
US-20110046186-A1 1-Substituted Pyridyl-Pyrazolyl Amide Compounds and Uses Thereof SHENYANG SCIENCREAT CHEMICALS CO., LTD (CN) 2011-02-24 — — US disclosed
US-20110046186-A1 1-Substituted Pyridyl-Pyrazolyl Amide Compounds and Uses Thereof SHENYANG SCIENCREAT CHEMICALS CO., LTD (CN) 2011-02-24 — — US disclosed
US-20110046186-A1 1-Substituted Pyridyl-Pyrazolyl Amide Compounds and Uses Thereof SHENYANG SCIENCREAT CHEMICALS CO., LTD (CN) 2011-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046186-A1 1-Substituted Pyridyl-Pyrazolyl Amide Compounds and Uses Thereof AADAC, DDT, PIR MAPT 3284/4885
US-20140243376-A1 O-AMINO BENZONITRILE COMPOUNDS, METHOD FOR PREPARING SAME AND USES THEREOF DBF4, BLVRB, DBN1 MAPT 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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