SCHEMBL11986154

SCHEMBL11986154

C=C(C)C(=O)OCOc1ccc(CCC(=O)Oc2ccc(S(=O)(=O)c3ccc(OC(=O)CCc4ccc(OCOC(=O)C(=C)C)cc4F)cc3)cc2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KMT2A Q03164 2/20 0.36
FFAR1 O14842 11/20 0.34
ELANE P08246 2/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986114 0.90 MAPT (0.41) PKMPOLBMAPTGAANPSR1
SCHEMBL11986161 0.84 PKM (0.36) PKMPOLBMAPTGAANPSR1
SCHEMBL11986143 0.84 FFAR1 (0.35) KMT2AFFAR1FFAR4
SCHEMBL11986159 0.84 KMT2A (0.43) PKMPOLBMAPTGAANPSR1
SCHEMBL11986151 0.82 MAPT (0.41) PKMPOLBMAPTGAANPSR1
SCHEMBL13932672 0.81 POLB (0.43) PKMPOLBMAPTGAANPSR1
SCHEMBL13289703 0.79 FFAR1 (0.38) MAPTFFAR1
SCHEMBL11986162 0.79 CA12 (0.40) PKMPOLBMAPTGAANPSR1
SCHEMBL13932765 0.79 MAPT (0.40) PKMPOLBMAPTGAANPSR1
SCHEMBL12154306 0.76 GAA (0.39) PKMPOLBMAPTGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-8419973-B2 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed