SCHEMBL11986258

SCHEMBL11986258

CC(C)(C)C1COC2C1OCC2C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15479069 1.00 THRB (0.32) THRBLMNA
SCHEMBL22419334 1.00 THRB (0.32) THRBLMNA
SCHEMBL22419345 0.87
SCHEMBL22419337 0.87
SCHEMBL16476096 0.87
SCHEMBL24900249 0.87
SCHEMBL20921353 0.87
SCHEMBL22722635 0.87
SCHEMBL22419335 0.87
SCHEMBL16981320 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535706-B2 Polycarbonate polyol compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2022-12-27 US disclosed
US-20210171708-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2021-06-10 US disclosed
US-10836859-B2 Polycarbonate polyol compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2020-11-17 US disclosed
US-10772964-B2 Composition comprising a polymer and a bioactive agent and method of preparing thereof PHAGELUX (CANADA), INC. (CA) 2020-09-15 US disclosed
US-20190233586-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. 2019-08-01 US disclosed
US-10301426-B2 Polycarbonate polyol compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2019-05-28 US disclosed
US-20180022869-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. 2018-01-25 US disclosed
US-9809678-B2 Polycarbonate polyol compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-11-07 US disclosed
US-20160264728-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-09-15 US disclosed
US-9376531-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2016-06-28 US disclosed
US-20150299386-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2015-10-22 US disclosed
US-9144579-B2 Polyesters and methods of use thereof RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-09-29 US disclosed
US-8921508-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2014-12-30 US disclosed
US-20140050692-A1 POLYESTERS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2014-02-20 US disclosed
US-20140046008-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2014-02-13 US disclosed
US-20130244864-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-09-19 US disclosed
US-8470956-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2013-06-25 US disclosed
US-20130066044-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-03-14 US disclosed
US-8247520-B2 Polycarbonate polyol compositions and methods NOVOMER, INC. (US) 2012-08-21 US disclosed
US-20110230580-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS Novomer, Inc (US) 2011-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230580-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS PARG, PUF60, PICALM THRB 4876/4885LMNA 2980/4885
US-20140050692-A1 POLYESTERS AND METHODS OF USE THEREOF TLR3, PTGES3, CD68 THRB 3220/4885LMNA 2049/4885
US-10772964-B2 Composition comprising a polymer and a bioactive agent and method of preparing thereof PRNP, PHOSPHO1, PPA1 THRB 2446/4885LMNA 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.