Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 8/20 | 0.32 |
| ▸ | DRD3 | P35462 | 8/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990779 | 0.74 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL912111 | 0.74 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL7399742 | 0.74 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL8317912 | 0.74 | DRD2 (0.53) | HTR2CDRD2DRD3 | |
| SCHEMBL7847793 | 0.73 | DRD2 (0.48) | HTR2CDRD2DRD3 | |
| SCHEMBL7846708 | 0.73 | DRD2 (0.48) | HTR2CDRD2DRD3 | |
| SCHEMBL29960480 | 0.73 | DRD2 (0.48) | HTR2CDRD2DRD3 | |
| SCHEMBL7846711 | 0.73 | DRD2 (0.48) | HTR2CDRD2DRD3 | |
| SCHEMBL6245152 | 0.73 | DRD2 (0.48) | HTR2CDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8904853 | 0.73 | DRD2 (0.52) | HTR2CDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247441-B2 | Chromene compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2012-08-21 | — | — | US | disclosed |
| US-20110021490-A1 | Chromene compounds, a process for their preparationand pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021490-A1 | Chromene compounds, a process for their preparationand pharmaceutical compositions containing them | CHRM3, CCKAR, ADRB3 | HTR2C 102/4885DRD2 239/4885DRD3 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.