Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12445455 | 0.95 | KDM4E (0.57) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11987320 | 0.89 | SMN1; SMN2 (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL4179426 | 0.88 | ATR (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL5344919 | 0.88 | SMN1; SMN2 (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11987336 | 0.85 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11987328 | 0.85 | HSD17B10 (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL13929667 | 0.84 | KDM4E (0.67) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL28098934 | 0.84 | ATR (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11987337 | 0.82 | ATR (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11987334 | 0.82 | CCR1 (0.46) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247087-B2 | Compound having oxadiazole ring structure bonded with aromatic heterocyclic ring and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-8247087-B2 | Compound having oxadiazole ring structure bonded with aromatic heterocyclic ring and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20090230849-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090230849-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1932842-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090230849-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE BONDED WITH AROMATIC HETEROCYCLIC RING AND ORGANIC ELECTROLUMINESCENT DEVICE | OXA1L, ORC3, OCIAD1 | KDM4E 1379/4885LMNA 2959/4885CCR1 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.