Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179426 | 0.94 | ATR (0.49) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL11987334 | 0.93 | CCR1 (0.46) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL11987337 | 0.93 | ATR (0.49) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL11987320 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL12445455 | 0.92 | KDM4E (0.57) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL11987326 | 0.92 | ATR (0.48) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL11987328 | 0.91 | HSD17B10 (0.49) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL11987343 | 0.88 | FABP1 (0.39) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL11987331 | 0.88 | KDM4E (0.52) | SMN1; SMN2LMNAKDM4ECCR1CCR5 | |
| SCHEMBL28098934 | 0.87 | ATR (0.54) | SMN1; SMN2LMNAKDM4ECCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282586-B1 | Dipyridine-based compound and the use thereof | LUMINESCENCE TECHNOLOGY CORP. (TW) | 2007-10-16 | — | — | US | disclosed |
| US-7282586-B1 | Dipyridine-based compound and the use thereof | LUMINESCENCE TECHNOLOGY CORP. (TW) | 2007-10-16 | — | — | US | disclosed |
| US-7282586-B1 | Dipyridine-based compound and the use thereof | LUMINESCENCE TECHNOLOGY CORP. (TW) | 2007-10-16 | — | — | US | disclosed |