Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 10/20 | 0.47 |
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11987320 | 0.94 | SMN1; SMN2 (0.50) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11987326 | 0.93 | ATR (0.48) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11987337 | 0.92 | ATR (0.49) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5337509 | 0.90 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL12445455 | 0.88 | KDM4E (0.57) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11987328 | 0.87 | HSD17B10 (0.49) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL4179426 | 0.87 | ATR (0.49) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5344919 | 0.87 | SMN1; SMN2 (0.48) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5340331 | 0.87 | RAB9A (0.63) | ATRNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11987331 | 0.84 | KDM4E (0.52) | ATRNPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045990-B | Phenanthroline derivatives and use thereof | 机光科技股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-106045990-A | Phenanthroline derivatives and use thereof | 机光科技股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106008498-A | Phenanthroline derivative and organic electroluminescent device using same | 机光科技股份有限公司 | 2016-10-12 | — | — | CN | disclosed |