SCHEMBL11987948

SCHEMBL11987948

CC(C)(C)c1ccc(N(c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc2)c2ccc(-c3nnc(-c4ccccc4)o3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ S1PR1 P21453 2/20 0.41
▸ KDM4E B2RXH2 6/20 0.39
▸ NPC1 O15118 6/20 0.39
▸ RAB9A P51151 6/20 0.39
▸ SMN1; SMN2 Q16637 6/20 0.39
▸ ALDH1A1 P00352 5/20 0.39
▸ HPGD P15428 5/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ POLB P06746 3/20 0.39
▸ TP53 P04637 2/20 0.39
▸ EGFR P00533 1/20 0.39
▸ TSPO P30536 1/20 0.38
▸ MAPT P10636 4/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ ATM Q13315 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987959 0.98 S1PR1 (0.41) S1PR1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL11987973 0.97 S1PR1 (0.41) S1PR1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL14465668 0.93 S1PR1 (0.42) S1PR1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL12680744 0.93 S1PR1 (0.47) S1PR1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL11987949 0.93 KDM4E (0.43) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13230198 0.92 S1PR1 (0.46) S1PR1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL2805039 0.92 KDM4E (0.42) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13230183 0.92 S1PR1 (0.46) S1PR1KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL11987952 0.92 KDM4E (0.42) KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL14465527 0.91 S1PR1 (0.45) S1PR1KDM4ENPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530658-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 — — US disclosed
US-8530658-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 — — US disclosed
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-11-29 — — US disclosed
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-11-29 — — US disclosed
US-8247575-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-21 — — US disclosed
US-8247575-B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-08-21 — — US disclosed
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237773-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 S1PR1 4853/4885KDM4E 3212/4885NPC1 3646/4885
US-20120302751-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 S1PR1 4853/4885KDM4E 3212/4885NPC1 3646/4885
US-20100237339-A1 Carbazole Derivative with Heteroaromatic Ring, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative with Heteroaromatic Ring SLC43A3, CRY1, VDAC3 S1PR1 4853/4885KDM4E 3212/4885NPC1 3646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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