⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874102 | 0.79 | DAO (0.39) | — | |
| SCHEMBL2321226 | 0.76 | PGR (0.49) | — | |
| SCHEMBL30104097 | 0.76 | PGR (0.44) | — | |
| SCHEMBL974266 | 0.75 | — | — | |
| SCHEMBL7964615 | 0.75 | — | — | |
| SCHEMBL14477102 | 0.73 | — | — | |
| SCHEMBL2319480 | 0.72 | PGR (0.46) | — | |
| SCHEMBL346857 | 0.72 | — | — | |
| SCHEMBL23006 | 0.72 | — | — | |
| SCHEMBL27709338 | 0.72 | DAO (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113337005-A | Novel thienyl-containing DOPO flame retardant and synthesis method and application thereof | 衡阳师范学院 | 2021-09-03 | — | — | CN | claimed |
| CN-101481359-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-07-15 | — | — | CN | claimed |
| CN-1348370-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2002-05-08 | — | — | CN | claimed |
| US-20260034093-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUMITOMO PHARMA AMERICA, INC. (US) | 2026-02-05 | — | — | US | disclosed |
| US-12473304-B2 | Heterocyclic PAD4 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-11-18 | — | — | US | disclosed |
| CN-115348961-B | Heterocyclic PAD4 inhibitors | 百时美施贵宝公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119330969-A | Benzimidazole compound, preparation method, application and pharmaceutical composition thereof | 四川省肿瘤医院 | 2025-01-21 | — | — | CN | disclosed |
| US-20240358675-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUMITOMO PHARMA AMERICA, INC. (US) | 2024-10-31 | — | — | US | disclosed |
| CN-118666618-A | Synthesis method of aromatic aldehyde iodo compound | 阜阳师范大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-118359638-A | Compound serving as RET kinase inhibitor and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118165002-A | Polycyclic compounds and methods of use thereof | 桑诺维恩药品公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-0095340-B1 | PROCESSES FOR MAKING 3-METHYLTHIOPHENE-2-CARBOXALDEHYDE AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1986-08-13 | — | — | EP | disclosed |
| US-4532243-A | Imidazo(1,2-a)pyrimidines and their salts useful for treating anxiety | ROUSSEL UCLAF (FR) | 1985-07-30 | — | — | US | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4476312-A | Processes for making 3-methylthiophene-2-carboxaldehyde and intermediates therefor | PFIZER INC. (US) | 1984-10-09 | — | — | US | disclosed |
| US-4471139-A | Processes for making 3-methylthiophene-2-carboxaldehyde and intermediates therefor | PFIZER INC. (US) | 1984-09-11 | — | — | US | disclosed |
| EP-0104104-A1 | Imidazo(1,2-a)pyrimidines and their salts, process and intermediates for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1984-03-28 | — | — | EP | disclosed |
| EP-0095340-A1 | Processes for making 3-methylthiophene-2-carboxaldehyde and intermediates therefor | PFIZER INC. (US) | 1983-11-30 | — | — | EP | disclosed |
| US-4273573-A | Agents for regulating plant growth using 2-thiazolone-5-carboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | disclosed |
| EP-0005204-A2 | Plant growth regulating compositions containing 2-thiazolon-5-carboxylic acid derivatives, their preparation and their application | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |