SCHEMBL30104097

SCHEMBL30104097

O=Cc1cc(-c2csc(C=O)c2)cs1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.44
CYP2A6 P11509 2/20 0.33
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379478 0.86 HDAC6 (0.44) PGRCYP2A6
SCHEMBL6057498 0.84 PGR (0.43) PGRCYP2A6
SCHEMBL6194738 0.84 LMNA (0.46) PGRCYP2A6
SCHEMBL15820746 0.82 ERN1 (0.43) PGRCYP2A6CCNCCDK8
SCHEMBL2320780 0.82 PGR (0.42) PGR
SCHEMBL2321226 0.82 PGR (0.49) PGRCYP2A6
SCHEMBL6192775 0.82 ERN1 (0.50) PGRCYP2A6
SCHEMBL12177559 0.82 ALAD (0.53) PGR
SCHEMBL29951347 0.81 ALAD (0.56) PGR
SCHEMBL6192738 0.79 ERN1 (0.47) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115353505-A Synthesis method of (3, 3 '-bithiophene) -4,4' -dicarboxaldehyde 上海应用技术大学 2022-11-18 CN disclosed