Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pemaglitazar SCHEMBL3971148 | 0.89 | PPARG (0.56) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL3971735 | 0.89 | PPARG (0.56) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL29908544 | 0.89 | PPARG (0.56) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL3971139 | 0.89 | PPARG (0.56) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL6902223 | 0.87 | PPARA (0.52) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL6902218 | 0.87 | PPARA (0.52) | PPARGPPARANPC1RAB9ASLC6A9 | |
| SCHEMBL3970938 | 0.87 | NPC1 (0.47) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL6904072 | 0.87 | PPARG (0.54) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL6904388 | 0.85 | PPARG (0.52) | PPARGPPARANPC1RAB9ASLC6A9 | |
| Pemaglitazar SCHEMBL6904078 | 0.85 | PPARG (0.52) | PPARGPPARANPC1RAB9ASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412326-B1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-08-22 | — | — | EP | disclosed |