Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.52 |
| ▸ | PPARG | P37231 | 11/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pemaglitazar SCHEMBL6902223 | 1.00 | PPARA (0.52) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL29908544 | 0.96 | PPARG (0.56) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL3971148 | 0.96 | PPARG (0.56) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL3971735 | 0.96 | PPARG (0.56) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL3971139 | 0.96 | PPARG (0.56) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL6904072 | 0.94 | PPARG (0.54) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL6904078 | 0.92 | PPARG (0.52) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL6904388 | 0.92 | PPARG (0.52) | PPARAPPARGPTPN1SLC6A9NPC1 | |
| Pemaglitazar SCHEMBL6903499 | 0.91 | PPARG (0.45) | PPARAPPARGPTPN1SLC6A9PPARD | |
| SCHEMBL3967738 | 0.90 | PPARG (0.62) | PPARAPPARGPTPN1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412326-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011819-A1 | BUTYRIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |