SCHEMBL11997819

SCHEMBL11997819

c1cc(-[n+]2ccsc2)cc(-[n+]2ccsc2)c1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9386159 0.86 CA12 (0.39) FFAR4ALDH1A1
SCHEMBL5065145 0.84 ALDH1A1 (0.38) FFAR4ALDH1A1
Bromide SCHEMBL4939222 0.82 ALDH1A1 (0.41) FFAR4ALDH1A1
SCHEMBL11997826 0.78 SLC22A2 (0.38) FFAR4ALDH1A1
SCHEMBL8863421 0.78 BCL2 (0.42) FFAR4ALDH1A1
SCHEMBL11997831 0.77 SLC22A2 (0.36) FFAR4ALDH1A1
SCHEMBL11997829 0.74 FFAR4 (0.35) FFAR4
SCHEMBL11995120 0.64 ACHE (0.36) ALDH1A1
SCHEMBL11997836 0.62 ADORA2A (0.40) ALDH1A1
SCHEMBL11997820 0.59 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8754232-B2 Methods of making bis-tridentate carbene complexes of ruthenium and osmium UNIVERSAL DISPLAY CORPORATION (US) 2014-06-17 — — US disclosed
US-20140021453-A1 METHODS OF MAKING BIS-TRIDENTATE CARBENE COMPLEXES OF RUTHENIUM AND OSMIUM UNIVERSAL DISPLAY CORPORATION (US) 2014-01-23 — — US disclosed
US-8563737-B2 Methods of making bis-tridentate carbene complexes of ruthenium and osmium UNIVERSAL DISPLAY CORPORATION (US) 2013-10-22 — — US disclosed
US-20120215000-A1 METHODS OF MAKING BIS-TRIDENTATE CARBENE COMPLEXES OF RUTHENIUM AND OSMIUM UNIVERSAL DISPLAY CORPORATION 2012-08-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120215000-A1 METHODS OF MAKING BIS-TRIDENTATE CARBENE COMPLEXES OF RUTHENIUM AND OSMIUM OCIAD2, OCIAD1, OSTC FFAR4 3811/4885ALDH1A1 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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