Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.64 |
| ▸ | HPGDS | O60760 | 3/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255701 | 0.85 | ACACB (0.65) | ACACB | |
| SCHEMBL12001230 | 0.85 | ACACB (0.83) | ACACB | |
| SCHEMBL12001587 | 0.85 | ACACB (0.67) | ACACB | |
| SCHEMBL13211073 | 0.84 | LMNA (0.53) | ACACBGRIA2 | |
| SCHEMBL255723 | 0.84 | ACACB (0.64) | ACACB | |
| SCHEMBL12001229 | 0.83 | ACACB (0.69) | ACACB | |
| SCHEMBL255721 | 0.82 | ACACB (0.58) | ACACB | |
| SCHEMBL12001047 | 0.81 | ACACB (0.70) | ACACB | |
| SCHEMBL12001050 | 0.81 | ACACB (0.70) | ACACB | |
| SCHEMBL256801 | 0.80 | ACACB (0.62) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214785-A1 | New compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214785-A1 | New compounds, pharmaceutical compositions and uses thereof | ABCG2, PGA5, PDE6G | ACACB 2257/4885HPGDS 129/4885GRIA2 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.