Sugi Predict

Sugi Predict / Compounds / Propylparaben

Propylparaben

Propylparaben

SCHEMBL1200262

CC(C)COC(=O)c1ccc(O)cc1.CCCOC(=O)c1ccc(O)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 4/20 0.78
▸ TSHR P16473 2/20 0.78
▸ ALDH1A1 P00352 2/20 0.78
▸ CHRM1 P11229 1/20 0.78
▸ SLC6A2 P23975 1/20 0.78
▸ KDR P35968 1/20 0.78
▸ TDP1 Q9NUW8 1/20 0.78
▸ LMNA P02545 2/20 0.64
▸ SMN1; SMN2 Q16637 2/20 0.64
▸ CYP1A2 P05177 1/20 0.64
▸ CYP2D6 P10635 1/20 0.64
▸ MAPK1 P28482 1/20 0.64
▸ CYP2C19 P33261 1/20 0.64
▸ NR1H2 P55055 1/20 0.64
▸ RNASEL Q05823 1/20 0.64
▸ ESR2 Q92731 2/20 0.57
▸ CA12 O43570 2/20 0.57
▸ CA1 P00915 2/20 0.57
▸ CA2 P00918 2/20 0.57
▸ CA7 P43166 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5164197 0.94 ALDH1A1 (0.66) ESR1TSHRALDH1A1CHRM1SLC6A2
Butylparaben SCHEMBL2526213 0.91 ESR1 (0.79) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL34633 0.90 ADRB2 (0.64) ESR1TSHRALDH1A1CHRM1SLC6A2
Propylparaben SCHEMBL10582852 0.89 ESR1 (0.86) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL30830422 0.89 ADRB2 (0.62) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL156746 0.89 ADRB2 (0.62) ESR1TSHRALDH1A1CHRM1SLC6A2
Propylparaben SCHEMBL977 0.88 ESR1 (1.00) ESR1TSHRALDH1A1CHRM1SLC6A2
Propylparaben SCHEMBL429594 0.88 ESR1 (1.00) ESR1TSHRALDH1A1CHRM1SLC6A2
Butylparaben SCHEMBL31213722 0.88 ESR1 (0.66) ESR1TSHRALDH1A1CHRM1SLC6A2
SCHEMBL11702741 0.88 ALDH1A1 (0.59) ESR1TSHRALDH1A1CHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9233066-B2 Active formulations based on plant extracts; phytocosmetic and/or phytotherapeutic formulations comprising the same method for Instituto Nacional de Pesquisa da Amazonia—INPA (BR) 2016-01-12 — — US claimed
US-20100284943-A1 Active Formulations Based on Plant Extracts; Phytocosmetic and/or Phytotherapeutic Formulations Comprising the Same Method For FUNDACAO UNIVERSIDADE DO AMAZONAS - FUA - UFAM (BR) 2010-11-11 — — US claimed
EP-2222271-A1 ACTIVE FORMULATIONS BASED ON ESSENTIAL OIL OF PLANTS OF THE GENUS PROTIUM, GUATTERIA, CYPERUS AND THE MIXTURE THEREOF Instituto Nacional De Pesquisa Da Amazônia - INPA (BR) 2010-09-01 — — EP claimed
WO-2009082797-A1 ACTIVE FORMULATIONS BASED ON ESSENTIAL OIL OF PLANTS OF THE GENUS PROTIUM, GUATTERIA, CYPERUS AND THE MIXTURE THEREOF INSTITUTO NACIONAL DE PESQUISA DA AMAZÔNIA - INPA (BR) 2009-07-09 — — WO claimed
EP-4025675-A1 A PERFUME OIL MIXTURE Symrise AG (DE) 2022-07-13 — — EP disclosed
EP-3982910-A1 A COOLING PREPARATION Symrise AG (DE) 2022-04-20 — — EP disclosed
EP-3911159-A1 AN ANTIMICROBIAL MIXTURE Symrise AG (DE) 2021-11-24 — — EP disclosed
EP-3852713-A1 COMPOSITIONS COMPRISING ODORLESS 1,2-PENTANEDIOL Symrise AG (DE) 2021-07-28 — — EP disclosed
WO-2020057761-A9 COMPOSITIONS COMPRISING ODORLESS 1,2-PENTANEDIOL SYMRISE AG (DE) 2021-05-06 — — WO disclosed
WO-2021043585-A1 A PERFUME OIL MIXTURE SYMRISE AG (DE) 2021-03-11 — — WO disclosed
WO-2020249216-A1 A COOLING PREPARATION SYMRISE AG (DE) 2020-12-17 — — WO disclosed
WO-2020147953-A1 AN ANTIMICROBIAL MIXTURE SYMRISE AG (DE) 2020-07-23 — — WO disclosed
WO-2020057761-A1 COMPOSITIONS COMPRISING ODORLESS 1,2-PENTANEDIOL SYMRISE AG (DE) 2020-03-26 — — WO disclosed
EP-2328542-B1 SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENS BASF SE (DE) 2018-04-25 — — EP disclosed
US-20170231889-A1 Sunscreen Compositions Comprising Colour Pigments BASF SE (DE) 2017-08-17 — — US disclosed
EP-2710996-A2 Sunscreen compositions comprising colour pigments BASF SE (DE) 2014-03-26 — — EP disclosed
US-7910119-B2 Cosmetic emulsions with long-term stability EVONIK GOLDSCHMIDT GMBH (DE) 2011-03-22 — — US disclosed
US-20110033400-A1 SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS BASF SE (US) 2011-02-10 — — US disclosed
US-20060204468-A1 Cosmetic emulsions with long-term stability GOLDSCHMIDT GMBH (DE) 2006-09-14 — — US disclosed
WO-2005070386-A1 BODY ART THE DEZAC GROUP LIMITED (GB) 2005-08-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110033400-A1 SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS TYR, ERCC1, ERCC4 ESR1 1893/4885TSHR 4121/4885ALDH1A1 221/4885
US-20170231889-A1 Sunscreen Compositions Comprising Colour Pigments TYR, ERCC1, ERCC4 ESR1 1893/4885TSHR 4121/4885ALDH1A1 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.