SCHEMBL12005408

SCHEMBL12005408

CC(C)(C)OC(=O)N1CCNCCN(C(=O)OC(C)(C)C)CCNCC1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MAPK1 P28482 1/20 0.49
HPGD P15428 1/20 0.49
RECQL P46063 1/20 0.46
EPHX1 P07099 1/20 0.46
NR1H2 P55055 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
EPHX2 P34913 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
GPR119 Q8TDV5 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8286 1.00 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDRECQL
SCHEMBL1225127 1.00 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDRECQL
SCHEMBL587550 1.00 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDRECQL
SCHEMBL2220355 0.98 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDRECQL
SCHEMBL14653343 0.98 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDRECQL
Ammonia Solution, Strong SCHEMBL18035416 0.98 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDRECQL
Hydrochloric Acid SCHEMBL1904026 0.98 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDRECQL
Hydrochloric Acid SCHEMBL4141237 0.98 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDRECQL
SCHEMBL132585 0.98 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDRECQL
SCHEMBL2934532 0.98 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024235128-A9 ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-06-19 WO disclosed
WO-2024235132-A9 COMPOUND HAVING BIOLOGICAL ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-06-19 WO disclosed
WO-2025087229-A1 LIGAND COMPOUND OF QUINOLINE STRUCTURE, RADIOACTIVE OR NON-RADIOACTIVE MARKER, AND USE 四川科伦博泰生物医药股份有限公司 2025-05-01 WO disclosed
WO-2025087466-A2 LIGAND COMPOUND OF QUINOLINE STRUCTURE, AND RADIOACTIVE OR NON-RADIOACTIVE MARKER THEREOF AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2025-05-01 WO disclosed
WO-2024235128-A1 ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-11-21 WO disclosed
WO-2024235132-A1 COMPOUND HAVING BIOLOGICAL ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-11-21 WO disclosed
EP-4087621-A1 MACROCYCLIC CHELATES AND USES THEREOF Fusion Pharmaceuticals Inc. (CA) 2022-11-16 EP disclosed
CN-115243729-A Macrocyclic chelates and their use 融合制药公司 2022-10-25 CN disclosed
US-20210395281-A1 MACROCYCLIC CHELATES AND USES THEREOF OXFORD FINANCE LLC 2021-12-23 US disclosed
US-20210395281-A1 MACROCYCLIC CHELATES AND USES THEREOF OXFORD FINANCE LLC 2021-12-23 US disclosed
EP-2495563-A1 DIAGNOSTIC AGENT FOR INFECTIOUS DISEASES Fujifilm RI Pharma Co., Ltd. (JP) 2012-09-05 EP disclosed
US-20120219500-A1 DIAGNOSTIC AGENT FOR INFECTIOUS DISEASES FUJIFILM RI PHARMA CO., LTD. (JP) 2012-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395281-A1 MACROCYCLIC CHELATES AND USES THEREOF PAICS, CLTC, CLTB USP2 2974/4885SMN1; SMN2 2853/4885MAPK1 4841/4885
US-20120219500-A1 DIAGNOSTIC AGENT FOR INFECTIOUS DISEASES NISCH, CNDP2, MYADM USP2 2163/4885SMN1; SMN2 2683/4885MAPK1 3395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.