SCHEMBL2220355

SCHEMBL2220355

CC(C)(C)OC(=O)N1CCNCCN(C(=O)OC(C)(C)C)CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPK1 P28482 1/20 0.48
HPGD P15428 1/20 0.47
EPHX2 P34913 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
RECQL P46063 1/20 0.45
EPHX1 P07099 1/20 0.45
NR1H2 P55055 1/20 0.45
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
THRB P10828 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132585 1.00 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL17297711 0.98 USP2 (0.55) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL1225127 0.98 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL12005408 0.98 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL587550 0.98 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL8286 0.98 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDEPHX2
Ammonia Solution, Strong SCHEMBL18035416 0.96 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL14653343 0.96 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDEPHX2
Hydrochloric Acid SCHEMBL1904026 0.96 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDEPHX2
Hydrochloric Acid SCHEMBL4141237 0.96 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230182088-A1 METHOD FOR PREPARING HIGH-SELECTIVITY LITHIUM-MAGNESIUM SEPARATION MEMBRANE TIANJIN UNIVERSITY (CN) 2023-06-15 US claimed
CN-114573598-B White She Tengxin (II) complex with high in-vivo and in-vitro activity and synthesis method and application thereof 玉林师范学院 2023-05-05 CN claimed
CN-115010915-A Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative 厦门赛诺邦格生物科技股份有限公司 2022-09-06 CN claimed
CN-114573598-A White leaf vine zinc (II) complex with high activity in vivo and in vitro and synthesis method and application thereof 玉林师范学院 2022-06-03 CN claimed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-112694608-A Six-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2021-04-23 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
EP-3315531-A1 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY Xiamen Sinopeg Biotech Co., Ltd. (CN) 2018-05-02 EP claimed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US claimed
US-12637398-B2 Radiohalogen prosthetic moieties and radiolabeled biomolecules DUKE UNIVERSITY (US) 2026-05-26 US disclosed
EP-4737504-A2 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND FORMULATION AND APPLICATION THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2026-05-06 EP disclosed
EP-4276090-B1 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND PREPARATION AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO LTD (CN) 2026-04-29 EP disclosed
EP-4321504-B1 PEGYLATED LIPID AND LIPOSOME MODIFIED THEREBY, AND PHARMACEUTICAL COMPOSITION COMPRISING LIPOSOME AND PREPARATION AND USE THEREOF XIAMEN SINOPEG BIOTECH CO LTD (CN) 2026-02-18 EP disclosed
US-20250144236-A1 NITROGEN-BRANCHED NON-LINEAR PEGYLATED LIPID AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2025-05-08 US disclosed
EP-1381392-A4 SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME TS CORP (KR) 2005-03-23 EP disclosed
CN-1531444-A Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using same ������������ʽ���� 2004-09-22 CN disclosed
EP-1381392-A1 SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME TS Corporation (KR) 2004-01-21 EP disclosed
US-20020165365-A1 Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same ARTZYME BIOTECH CORPORATION (KR) 2002-11-07 US disclosed
WO-2002085413-A1 SYNTHETIC CATALYST FOR SELECTIVE CLEAVAGE OF PROTEIN AND METHOD FOR SELECTIVE CLEAVAGE OF PROTEIN USING THE SAME TS CORPORATION (KR) 2002-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250144236-A1 NITROGEN-BRANCHED NON-LINEAR PEGYLATED LIPID AND APPLICATION THEREOF LMNB1, SSB, LDLR USP2 2716/4885SMN1; SMN2 2273/4885MAPK1 2111/4885
US-12637398-B2 Radiohalogen prosthetic moieties and radiolabeled biomolecules CD47, KLK3, SHBG USP2 3562/4885SMN1; SMN2 4594/4885MAPK1 2709/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 USP2 1433/4885SMN1; SMN2 3017/4885MAPK1 1476/4885
US-20020165365-A1 Synthetic catalyst for selective cleavage of protein and method for selective cleavage of protein using the same CPN1, RNPEP, ANPEP USP2 1855/4885SMN1; SMN2 3815/4885MAPK1 4547/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 USP2 1433/4885SMN1; SMN2 3017/4885MAPK1 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.