Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 13/20 | 0.46 |
| ▸ | CA12 | O43570 | 12/20 | 0.46 |
| ▸ | CA1 | P00915 | 12/20 | 0.46 |
| ▸ | CA9 | Q16790 | 10/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 6/20 | 0.42 |
| ▸ | CA5A | P35218 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12006745 | 1.00 | NR3C1 (0.50) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL12005604 | 1.00 | NR3C1 (0.50) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL25517909 | 0.84 | CA2 (0.41) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL25495692 | 0.84 | PPARD (0.37) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL25495689 | 0.84 | CA2 (0.41) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL25495547 | 0.84 | PPARD (0.37) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL25496574 | 0.84 | PPARD (0.34) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL21848209 | 0.83 | CYP2D6 (0.53) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL22614597 | 0.83 | CA2 (0.40) | NR3C1FYNADRA2AADORA3ADRA2B | |
| SCHEMBL25496577 | 0.82 | PPARD (0.33) | NR3C1FYNADRA2AADORA3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018370-B2 | Derivatives of uridine phosphate and their uses in protein binding assays | KING'S COLLEGE LONDON OF STRAND (GB) | 2015-04-28 | — | — | US | disclosed |
| US-20120219963-A1 | DERIVATIVES OF URIDINE PHOSPHATE AND THEIR USES IN PROTEIN BINDING ASSAYS | KING'S COLLEGE LONDON OF STRAND (GB) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219963-A1 | DERIVATIVES OF URIDINE PHOSPHATE AND THEIR USES IN PROTEIN BINDING ASSAYS | OGA, OSTC, UPP1 | NR3C1 2040/4885FYN 2795/4885ADRA2A 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.