SCHEMBL1200699

SCHEMBL1200699

CC1Cc2ccccc2-c2ccccc2CC1C

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.56
NOS3 P29474 2/20 0.50
NOS2 P35228 2/20 0.50
TSHR P16473 1/20 0.50
HTR2A P28223 3/20 0.45
HTR1A P08908 1/20 0.44
DRD2 P14416 1/20 0.44
METAP1 P53582 2/20 0.41
HTR2C P28335 2/20 0.40
HTR2B P41595 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31236843 0.86 IDO1 (0.46) ACHENOS3NOS2TSHR
SCHEMBL31236844 0.86 IDO1 (0.46) ACHENOS3NOS2TSHR
SCHEMBL16691536 0.78 ACHE (0.66) ACHENOS3NOS2TSHRHTR2A
SCHEMBL3054005 0.78 ACHE (0.66) ACHENOS3NOS2TSHRHTR2A
SCHEMBL8941781 0.77 ACHE (0.59) ACHENOS3NOS2TSHRHTR2A
SCHEMBL11776080 0.75 ACHE (0.61) ACHENOS3NOS2TSHRHTR2A
SCHEMBL13802325 0.74 HTR2A (0.45) ACHENOS3NOS2TSHRHTR2A
SCHEMBL20402534 0.74 PLAU (0.54) ACHENOS3NOS2TSHRHTR2A
SCHEMBL1699526 0.72 ACHE (0.58) ACHENOS3NOS2TSHRMETAP1
SCHEMBL9752693 0.72 ACHE (1.00) ACHENOS3NOS2TSHRMETAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110046217-A1 USE OF 2,2'-CYCLOLIGNANS FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS GREENTECH (FR) 2011-02-24 US claimed
EP-2190403-A1 USE OF 2,2'-CYCLOLIGNANES FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS Greentech (FR) 2010-06-02 EP claimed
WO-2009027330-A1 USE OF 2,2'-CYCLOLIGNANES FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS GREENTECH (FR) 2009-03-05 WO claimed
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 US disclosed
EP-3732994-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2022-11-09 EP disclosed
EP-3466930-B1 REDUCED SODIUM FOOD PRODUCT GEN MILLS INC (US) 2022-07-20 EP disclosed
EP-3732994-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2020-11-04 EP disclosed
US-20200281236-A1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2020-09-10 US disclosed
EP-3366677-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2020-09-09 EP disclosed
EP-3466930-A1 REDUCED SODIUM FOOD PRODUCT GENERAL MILLS, INC. (US) 2019-04-10 EP disclosed
US-20190090520-A1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2019-03-28 US disclosed
WO-2014124201-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124193-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124212-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
US-20110046217-A1 USE OF 2,2'-CYCLOLIGNANS FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS GREENTECH (FR) 2011-02-24 US disclosed
US-20110046217-A1 USE OF 2,2'-CYCLOLIGNANS FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS GREENTECH (FR) 2011-02-24 US disclosed
EP-2190403-A1 USE OF 2,2'-CYCLOLIGNANES FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS Greentech (FR) 2010-06-02 EP disclosed
EP-2190403-A1 USE OF 2,2'-CYCLOLIGNANES FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS Greentech (FR) 2010-06-02 EP disclosed
WO-2009027330-A1 USE OF 2,2'-CYCLOLIGNANES FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS GREENTECH (FR) 2009-03-05 WO disclosed
WO-2009027330-A1 USE OF 2,2'-CYCLOLIGNANES FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS GREENTECH (FR) 2009-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046217-A1 USE OF 2,2'-CYCLOLIGNANS FOR INDUCING, RESTORING OR STIMULATING THE PIGMENTATION OF THE SKIN, HAIR OR HAIRS TYR, MC1R, MCHR2 ACHE 1310/4885NOS3 1550/4885NOS2 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.