Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316954 | 0.86 | TSHR (0.38) | CYP2C19TSHRCHRM1KIF11SMN1; SMN2 | |
| SCHEMBL5788804 | 0.84 | CYP2C19 (0.43) | CYP2C19HIF1ATSHRDAOKIF11 | |
| SCHEMBL1143875 | 0.84 | CYP2C19 (0.43) | CYP2C19HIF1ATSHRDAOKIF11 | |
| SCHEMBL28888513 | 0.81 | CYP2C19 (0.48) | CYP2C19HIF1ATSHRHMGCRCHRM1 | |
| SCHEMBL5929581 | 0.81 | CHRM3 (0.39) | CYP2C19HIF1ATSHRCHRM1DAO | |
| SCHEMBL27862588 | 0.80 | CYP2C19 (0.51) | CYP2C19HIF1ATSHRCHRM1DAO | |
| SCHEMBL9014854 | 0.79 | CHRM3 (0.35) | CYP2C19TSHRSMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL28671879 | 0.79 | ESR1 (0.41) | CYP2C19TSHRCHRM1SMN1; SMN2CYP2D6 | |
| SCHEMBL9906158 | 0.79 | ESR1 (0.41) | CYP2C19TSHRCHRM1SMN1; SMN2CYP2D6 | |
| SCHEMBL28671877 | 0.79 | ESR1 (0.41) | CYP2C19TSHRCHRM1SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893281-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| US-20060264641-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | BERENDES FRANK | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264641-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | CYP2C19 155/4885HIF1A 540/4885TSHR 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.