SCHEMBL120089

SCHEMBL120089

O=C(Oc1c(Cl)cc(Cl)cc1Cl)Oc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
ALDH1A1 P00352 4/20 0.42
TSHR P16473 4/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP3A4 P08684 1/20 0.42
RECQL P46063 1/20 0.42
AKR1C4 P17516 1/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
KMT2A Q03164 3/20 0.39
TPMT P51580 1/20 0.37
HPGD P15428 1/20 0.37
CASP1 P29466 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317719 0.87 CA1 (0.46) CA1CA2CA9ALDH1A1TSHR
SCHEMBL19546119 0.87 ALDH1A1 (0.42) CA1CA2CA9ALDH1A1TSHR
Hydrogen Peroxide SCHEMBL29022846 0.85 CA1 (0.45) CA1CA2CA9ALDH1A1TSHR
SCHEMBL9244734 0.84 STK39 (0.45) ALDH1A1KMT2AMAPTTDP1
SCHEMBL27929671 0.83 CA1 (0.43) CA1CA2CA9ALDH1A1TSHR
SCHEMBL10447737 0.83 CA1 (0.43) CA1CA2CA9ALDH1A1TSHR
SCHEMBL17662461 0.82 TDP1 (0.39) CA1CA2CA9ALDH1A1HSD17B10
SCHEMBL20445555 0.81 CA1 (0.42) CA1CA2CA9ALDH1A1TSHR
SCHEMBL17278029 0.81 CA1 (0.47) CA1CA2CA9ALDH1A1TSHR
SCHEMBL1499174 0.81 CA1 (0.42) CA1CA2CA9ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7893274-B2 Process for producing amino acid N-carboxyanhydride JSR CORPORATION (JP) 2011-02-22 US claimed
EP-1399498-B1 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2006-06-21 EP claimed
EP-1353971-B1 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2005-05-11 EP claimed
EP-1504048-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-02-09 EP claimed
EP-1399498-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2004-03-24 EP claimed
EP-1360221-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-12 EP claimed
EP-1358246-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-05 EP claimed
EP-1358247-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-05 EP claimed
WO-2003087190-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-10-23 WO claimed
EP-1353971-A2 MELT POLYCARBONATE CATALYST SYSTEMS General Electric Company (US) 2003-10-22 EP claimed
US-6323304-B1 CONTACTING A DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF CATALYST COMPRISED OF ALKALI OR ALKALINE EARTH METAL-TRANSITION METAL FLUORIDE COMPOUND AND IN PRESENCE OF COCATALYST GENERAL ELECTRIC COMPANY 2001-11-27 US claimed
US-6303737-B1 POLYCONDENSATION CATALYSTS WHICH ARE SALTS OF CERTAIN PHENANTHROLINE COMPOUNDS; EXCELLENT POLYMERIZATION RATES; REDUCING THE LEVEL OF BRANCHING SIDE REACTION, I.E., FORMATION OF FRIES PRODUCT GENERAL ELECTRIC COMPANY 2001-10-16 US claimed
US-6291631-B1 CONTACTING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE POLYMERIZATION CATALYST UNDER POLYCARBONATE MELT POLYMERIZATION CONDITIONS GENERAL ELECTRIC COMPANY 2001-09-18 US claimed
EP-0594175-B1 Process for producing aromatic polycarbonate MITSUBISHI CHEM CORP (JP) 1997-06-18 EP claimed
US-5391693-A Copolymerization of aromatic diol and 9,9-bis(4-hydroxyphenyl) fluorene derivative in presence of phosgene or derivatives in inert solvent in presence of potassium hydroxide IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
US-5391691-A Melt condensing am aromatic diol compound and a carbonic acid diester in the presence of an interesterification catalyst and co-presence of an organosilicon compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
EP-0594175-A1 Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1994-04-27 EP claimed
EP-0492003-A1 Process for the preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-01 EP claimed
US-5025083-A Process for preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-18 US claimed
EP-0382250-A2 Process for preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1990-08-16 EP claimed