Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12009091 | 0.92 | ALDH1A1 (0.56) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL18545565 | 0.92 | ALDH1A1 (0.56) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL18545447 | 0.88 | TCF4 (0.58) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL12009075 | 0.88 | TCF4 (0.58) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL12009101 | 0.88 | TCF4 (0.58) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL18545575 | 0.84 | TCF4 (0.58) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL12009076 | 0.84 | TCF4 (0.58) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL12009051 | 0.83 | TCF4 (0.70) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL18545491 | 0.83 | TCF4 (0.70) | TCF4CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL12009081 | 0.83 | TCF4 (0.64) | TCF4CTNNB1HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252823-B2 | Oxazole and thiazole compounds as beta-catenin modulators and uses thereof | NEW YORK UNIVERSITY (US) | 2012-08-28 | — | — | US | disclosed |