SCHEMBL1201044

SCHEMBL1201044

[C]#Cc1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28726262 0.69
SCHEMBL2852858 0.67
SCHEMBL195035 0.67
SCHEMBL1324980 0.67
SCHEMBL534717 0.67
SCHEMBL28061488 0.67 CLK4 (0.38)
SCHEMBL151679 0.67
Hydrochloric Acid SCHEMBL7414247 0.65
SCHEMBL30827004 0.65
SCHEMBL21670004 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3440054-A1 PYRROLE DERIVATIVES Hua Medicine (Shanghai) Ltd. (CN) 2019-02-13 EP claimed
WO-2017173604-A1 PYRROLE DERIVATIVES HUA MEDICINE (SHANGHAI) LTD. (CN) 2017-10-12 WO claimed
US-5712264-A 17-spiromethylene steroids AKZO NOBEL N.V. (NL) 1998-01-27 US claimed
US-20230159561-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES FMC CORP (US) 2023-05-25 US disclosed
US-11578085-B2 Heterocycle-substituted bicyclic azole pesticides FMC CORPORATION (US) 2023-02-14 US disclosed
EP-4105209-A2 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES FMC Corporation (US) 2022-12-21 EP disclosed
EP-3424919-B1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES FMC CORP (US) 2022-04-27 EP disclosed
US-20210017192-A1 HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES FMC CORP (US) 2021-01-21 US disclosed
US-10822351-B2 Heterocycle-substituted bicyclic azole pesticides FMC CORPORATION (US) 2020-11-03 US disclosed
WO-2020130214-A1 NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF 한국과학기술연구원 2020-06-25 WO disclosed
US-10647692-B2 Heterocycle-substituted bicyclic azole pesticides FMC CORPORATION (US) 2020-05-12 US disclosed
US-20050267111-A1 Pharmaceutical compositions and methods for use DULL GARY M 2005-12-01 US disclosed
US-6890935-B2 Pharmaceutical compositions and methods for use TARGACEPT, INC. (US) 2005-05-10 US disclosed
WO-2002088114-A2 HETEROARYL OFEFINIC AZACYCLIC AND HETEROARYL ACETYLENIC AZACYCLIC COMPOUNDS FOR THE TREATMENT OF CNS DISORDERS TARGACEPT, INC. (US) 2002-11-07 WO disclosed
US-20020058652-A1 Pharmaceutical compositions and methods for use TARGACEPT, INC. 2002-05-16 US disclosed
WO-2002036548-A2 METHOD FOR STEREOSELECTIVELY PRODUCING HYDRAZINO CYCLOALKENES AND DIAMINO CYCLOALKANES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-10 WO disclosed
US-5573999-A FUNGICIDES AND INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-12 US disclosed
US-5538940-A FUNGICIDE, MITICIDE, INSECTICIDE BASF AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0525516-B1 Derivatives of beta substituted cinnomic acid BASF AG (DE) 1995-09-27 EP disclosed
EP-0525516-A2 Derivatives of beta substituted cinnomic acid BASF Aktiengesellschaft (DE) 1993-02-03 EP disclosed