SCHEMBL195035

SCHEMBL195035

O=[C]c1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15870986 0.72 HDAC8 (0.39)
SCHEMBL16861487 0.67
SCHEMBL6965540 0.67
SCHEMBL28061488 0.67 CLK4 (0.38)
SCHEMBL1324980 0.67
SCHEMBL1201044 0.67
SCHEMBL534717 0.67
SCHEMBL2852858 0.67
SCHEMBL151679 0.67
SCHEMBL4653 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024015569-A2 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION JNANA THERAPEUTICS INC. (US) 2024-01-18 WO claimed
WO-2024015574-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION JNANA THERAPEUTICS INC. (US) 2024-01-18 WO claimed
WO-2023171665-A1 PIPERIDINONE DERIVATIVE OR SALT THEREOF, HARMFUL ORGANISM CONTROL AGENT CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME 株式会社ADEKA 2023-09-14 WO claimed
US-20230219964-A1 ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES SYDDANSK UNIVERSITET (DK) 2023-07-13 US claimed
WO-2023122267-A2 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION JNANA THERAPEUTICS INC. (US) 2023-06-29 WO claimed
EP-4143172-A1 ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES Syddansk Universitet (DK) 2023-03-08 EP claimed
CN-115720579-A Antibacterial and antifungal pleuromutilin conjugates 赛丹思科大学 2023-02-28 CN claimed
CN-109810110-B Compound with 2-aminopyrimidine structure, preparation method and application thereof 中国科学院上海药物研究所 2023-01-24 CN claimed
EP-3609883-B1 FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2022-06-29 EP claimed
US-11242335-B2 Fluorine-substituted indazole compounds and uses thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2022-02-08 US claimed
WO-1997009319-A1 SUBSTITUTED 1-AMINO-3-PHENYLURACIL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-13 WO claimed
EP-0601486-A1 Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation LUCKY LTD. (KR) 1994-06-15 EP claimed
EP-0547140-A4 IMMUNOSUPPRESSANT COMPOSITION 1993-10-13 EP claimed
EP-0547140-A1 IMMUNOSUPPRESSANT COMPOSITION THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1993-06-23 EP claimed
US-5190939-A Antihypoxic ADIR ET COMPAGNIE (FR) 1993-03-02 US claimed
WO-1992004055-A1 IMMUNOSUPPRESSANT COMPOSITION THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1992-03-19 WO claimed
US-5021421-A Psychotropic agents DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1991-06-04 US claimed
US-4985436-A PANCRATISTATIN, PLANT EXTRACTS ARIZONA BOARD OF REGENTS (US) 1991-01-15 US claimed
US-4866071-A ADMINISTERING PANCRATISTATIN AND 7-DEOXYNARCICLASINE ARIZONA BOARD OF REGENTS (US) 1989-09-12 US claimed
US-4708732-A 2-(pyrimidinecarbonyl)-1,3-cyclohexanediones and their use as herbicidal agents STAUFFER CHEMICAL COMPANY (US) 1987-11-24 US claimed