Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.69 |
| ▸ | THRB | P10828 | 10/20 | 0.69 |
| ▸ | BLM | P54132 | 10/20 | 0.69 |
| ▸ | RECQL | P46063 | 8/20 | 0.69 |
| ▸ | TOP2A | P11388 | 6/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.69 |
| ▸ | HTT | P42858 | 6/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.69 |
| ▸ | STAT6 | P42226 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12690574 | 1.00 | MEN1 (0.69) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL13351681 | 0.94 | EBP (0.70) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL13154315 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL22970097 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL17705921 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL3839149 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL17899511 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL12022391 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL13181351 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL18816263 | 0.92 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252740-B2 | Thermally-targeted delivery of medicaments including doxorubicin | THE UNIVERSITY OF MISSISSIPPI MEDICAL CENTER (US) | 2012-08-28 | — | — | US | disclosed |
| US-20100022466-A1 | THERMALLY-TARGETED DELIVERY OF MEDICAMENTS INCLUDING DOXORUBICIN | THE UNIVERSITY OF MISSISSIPPI MEDICAL CENTER | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022466-A1 | THERMALLY-TARGETED DELIVERY OF MEDICAMENTS INCLUDING DOXORUBICIN | ENPEP, LNPEP, ERAP1 | MEN1 2761/4885KMT2A 3472/4885THRB 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.