Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | GSK3B | P49841 | 2/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 1.00 |
| ▸ | UBE2N | P61088 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 0.88 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.79 |
| ▸ | XDH | P47989 | 2/20 | 0.73 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.69 |
| ▸ | KDM1A | O60341 | 2/20 | 0.66 |
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naringin SCHEMBL30073709 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL20383126 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL16656151 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL20386954 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL2614060 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL16592383 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL13237107 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL23431 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL14114613 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM | |
| Naringin SCHEMBL30383784 | 1.00 | PTPN1 (1.00) | PTPN1GSK3BCYP19A1UBE2NPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120924-B1 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2016-03-09 | — | — | EP | disclosed |
| CN-104706855-A | Preparation methods and application of Jichuan decoction traditional Chinese medicine extract | JIANGSU HAIWANG HEALTH BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-06-17 | — | — | CN | disclosed |
| US-20120251643-A1 | ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2012-10-04 | — | — | US | disclosed |
| US-20110045108-A1 | ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2011-02-24 | — | — | US | disclosed |
| EP-2120924-A2 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | Zadec APS (DK) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110552-A9 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008110552-A2 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2008-09-18 | — | — | WO | disclosed |
| US-20040038914-A1 | Flavone/ flavanone derivatives for the systemic treatment and prophlaxis of uv-induced dermatoses | KRUTMANN JEAN (DE) | 2004-02-26 | — | — | US | disclosed |
| EP-1085865-A1 | USE OF CYTOPROTECTANTS | Seglen, Per (NO) | 2001-03-28 | — | — | EP | disclosed |
| WO-2000000191-A1 | USE OF CYTOPROTECTANTS | SEGLEN PER (NO) | 2000-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045108-A1 | ANTI-DIABETIC EXTRACT OF HONEYBUSH | IAPP, DPP4, DPP3 | PTPN1 2676/4885GSK3B 1949/4885CYP19A1 4557/4885 |
| US-20120251643-A1 | ANTI-DIABETIC EXTRACT OF HONEYBUSH | IAPP, DPP4, DPP3 | PTPN1 2676/4885GSK3B 1949/4885CYP19A1 4557/4885 |
| US-20040038914-A1 | Flavone/ flavanone derivatives for the systemic treatment and prophlaxis of uv-induced dermatoses | COLGALT1, PNN, F2 | PTPN1 2605/4885GSK3B 2515/4885CYP19A1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.