Naringin

Naringin

SCHEMBL23431

C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)OC(c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 1.00
GSK3B P49841 2/20 1.00
CYP19A1 P11511 2/20 1.00
UBE2N P61088 1/20 1.00
PKM P14618 1/20 0.88
SLCO2B1 O94956 2/20 0.79
XDH P47989 2/20 0.73
SYNJ2 O15056 1/20 0.69
KDM1A O60341 2/20 0.66
DPP4 P27487 1/20 0.66
TDP1 Q9NUW8 2/20 0.62
POLB P06746 1/20 0.62
CALM1 P0DP23 1/20 0.62
CACNA1B Q00975 1/20 0.62
APBA1 Q02410 1/20 0.62
CTDSP1 Q9GZU7 1/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
TRPA1 O75762 1/20 0.57
P4HB P07237 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naringin SCHEMBL30073709 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL20383126 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL16656151 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL20386954 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL2614060 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL16592383 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL13237107 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL14114613 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL1201445 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL30383784 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 21530 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748368-A1 COMPOSITION FOR ORAL HYGIENE PRODUCTS COMPRISING N-CETYLPYRIDINIUM CHLORIDE, A FLAVONOID AND A POLYMER Curaden AG (CH) 2026-05-27 EP claimed
CN-122075510-A High-activity epiglottis blood stasis removing decoction effective part and application thereof in preparing cough relieving pharmaceutical composition 2026-05-26 CN claimed
CN-122081102-A Microbial strain for de novo synthesis of gardenia flavin B and application of microbial strain in production of polymethoxy flavonoid compound 2026-05-26 CN claimed
CN-122075511-A Application of vildagliptin combined naringin in preparation of preparation for preventing and/or treating radiation lung injury 2026-05-26 CN claimed
CN-122094662-A Lime (citrus aurantium) extracts and their use as cosmetic agents 2026-05-26 CN claimed
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component Doane Technology Group LLC (US) 2026-05-26 US claimed
CN-122075567-A A composition containing herba Silybi Mariani extract and Akk bacteria 2026-05-26 CN claimed
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof 2026-05-26 CN claimed
CN-117903219-B Preparation method of phlorizin-4' -beta-neohesperidin GUILIN LAYN NATURAL INGREDIENTS CORP. (CN) 2026-05-26 CN claimed
WO-2026107262-A1 PROLONGED, SCAFFOLD-MEDIATED DELIVERY OF ANGIOGENIC COMPOUNDS EFEMORAL MEDICAL, INC. (US) 2026-05-21 WO claimed
US-4514427-A ION EXCHANGING USING A CATIONIC STYRENE POLYMER MITCO WATER LABORATORIES INC. (US) 1985-04-30 US claimed
EP-0067913-B1 COMPOSITION FOR THE TREATMENT OF ACNE RUSH-HAMPTON INDUSTRIES, INC. (US) 1984-12-05 EP claimed
US-4479972-A LEMON, ORANGE GENERAL FOODS CORPORATION (US) 1984-10-30 US claimed
EP-0067913-A1 Composition for the treatment of acne RUSH-HAMPTON INDUSTRIES, INC. (US) 1982-12-29 EP claimed
EP-0052086-A1 Process for producing flavone derivatives with medicinal activity BONOMELLI S.p.A. (IT) 1982-05-19 EP claimed
US-4297348-A USING NARINGIN, NARINGENIN AND PARTIALLY HYDROLYZED NARINGIN RUSH-HAMPTON INDUSTRIES, INC. (US) 1981-10-27 US claimed
US-4277464-A ANTICARIES AGENTS GENERAL FOODS CORPORATION (US) 1981-07-07 US claimed
EP-0027623-A1 Composition for the control of suckling mastitis and pyogenes mastitis in cattle Henkel Kommanditgesellschaft auf Aktien (DE) 1981-04-29 EP claimed
US-4238483-A Antimicrobial compositions of matter and a process for preparing antimicrobial compositions of matter from naturally occurring flavanoid glycosides RUSH-HAMPTON INDUSTRIES, INC. 1980-12-09 US claimed
US-3934047-A Taste modifier for artificial sweeteners GENERAL FOODS CORPORATION (US) 1976-01-20 US claimed