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Sugi Predict / Compounds / Naringin

Naringin

Naringin

SCHEMBL16656151

C[C@@H]1O[C@@H](O[C@H]2[C@@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 3/20 1.00
▸ GSK3B P49841 2/20 1.00
▸ CYP19A1 P11511 2/20 1.00
▸ UBE2N P61088 1/20 1.00
▸ PKM P14618 1/20 0.88
▸ SLCO2B1 O94956 2/20 0.79
▸ XDH P47989 2/20 0.73
▸ SYNJ2 O15056 1/20 0.69
▸ KDM1A O60341 2/20 0.66
▸ DPP4 P27487 1/20 0.66
▸ TDP1 Q9NUW8 2/20 0.62
▸ POLB P06746 1/20 0.62
▸ CALM1 P0DP23 1/20 0.62
▸ CACNA1B Q00975 1/20 0.62
▸ APBA1 Q02410 1/20 0.62
▸ CTDSP1 Q9GZU7 1/20 0.62
▸ MEN1 O00255 1/20 0.62
▸ KMT2A Q03164 1/20 0.62
▸ TRPA1 O75762 1/20 0.57
▸ P4HB P07237 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naringin SCHEMBL30073709 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL20383126 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL20386954 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL2614060 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL16592383 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL13237107 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL23431 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL14114613 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL1201445 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM
Naringin SCHEMBL30383784 1.00 PTPN1 (1.00) PTPN1GSK3BCYP19A1UBE2NPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012120-B2 Production process of toner for electrostatic image development KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2015-04-21 — — US disclosed
US-9012120-B2 Production process of toner for electrostatic image development KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2015-04-21 — — US disclosed