Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12014564 | 0.98 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014543 | 0.93 | MAPK9 (0.46) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014544 | 0.92 | PIK3CA (0.47) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014584 | 0.92 | PIK3CA (0.47) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014560 | 0.87 | MAPT (0.43) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014541 | 0.86 | PIK3CA (0.41) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014509 | 0.85 | MAPT (0.40) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL13658716 | 0.85 | KDM4E (0.50) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014563 | 0.84 | CYP1A2 (0.42) | ALDH1A1MAPTHPGDKDM4ECYP11B1 | |
| SCHEMBL12014568 | 0.84 | HPRT1 (0.40) | ALDH1A1MAPTHPGDCYP11B1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2011054442-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, DDT, ERCC1 | ALDH1A1 261/4885MAPT 1295/4885HPGD 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.