Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12014607 | 0.93 | MAPT (0.42) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL19271418 | 0.91 | HPRT1 (0.50) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL12014510 | 0.90 | MAPT (0.42) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL17995351 | 0.89 | HPRT1 (0.48) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL12014511 | 0.88 | MAPT (0.39) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL12655934 | 0.88 | SOS1 (0.41) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL12014504 | 0.87 | HSD17B10 (0.42) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL26031573 | 0.86 | TSHR (0.46) | MAPTLMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL20624260 | 0.85 | ESR1 (0.38) | MAPTLMNASMN1; SMN2ESR1ESR2 | |
| SCHEMBL12014609 | 0.85 | MAPT (0.38) | MAPTLMNASMN1; SMN2NPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, DDT, ERCC1 | MAPT 1295/4885LMNA 2254/4885SMN1; SMN2 3045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.