Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12014657 | 0.93 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL12014510 | 0.87 | MAPT (0.42) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL12014503 | 0.86 | KDM4E (0.47) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL12014515 | 0.85 | MAPT (0.41) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL19271418 | 0.85 | HPRT1 (0.50) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL19168408 | 0.84 | SOS1 (0.43) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL19167515 | 0.84 | HSD17B1 (0.44) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL12014618 | 0.84 | MAPT (0.40) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL12014504 | 0.84 | HSD17B10 (0.42) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL17995351 | 0.83 | HPRT1 (0.48) | MAPTKDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2011054442-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, DDT, ERCC1 | MAPT 1295/4885KDM4E 3591/4885ALDH1A1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.