Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 6/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.53 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | KRAS | P01116 | 2/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24247659 | 1.00 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL12087512 | 1.00 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL12590129 | 1.00 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL4369228 | 1.00 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL4371108 | 0.92 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL17972356 | 0.91 | HINT1 (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL17976623 | 0.91 | HINT1 (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL23679991 | 0.91 | HINT1 (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL22883381 | 0.91 | HINT1 (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL16359926 | 0.91 | HINT1 (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220649-A1 | MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220649-A1 | MODIFIED DOUBLE-STRANDED POLYNUCLEOTIDE | POLM, POLN, PNKP | HINT1 2414/4885NT5E 104/4885GSK3A 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.