Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 6/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.53 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24247659 | 0.92 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL4369228 | 0.92 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL12590129 | 0.92 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL12015186 | 0.92 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL12087512 | 0.92 | HINT1 (0.63) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL12031119 | 0.91 | HPGD (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL18512866 | 0.91 | HPGD (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL26515 | 0.91 | HPGD (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL16198946 | 0.91 | HPGD (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL12300426 | 0.91 | HPGD (0.61) | HINT1NT5EGSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010659-A2 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | Epicentre Technologies (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007120863-A2 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | EPICENTRE TECHNOLOGIES (US) | 2007-10-25 | — | — | WO | claimed |
| WO-2024133884-A2 | OPTIMIZED TAILING OF MESSENGER RNA | SANOFI (FR) | 2024-06-27 | — | — | WO | disclosed |
| CN-114929288-A | Synthetic modified RNA and uses thereof | 西奈山伊坎医学院 | 2022-08-19 | — | — | CN | disclosed |
| US-9115380-B2 | Kits and methods for generating 5′ capped RNA | CELLSCRIPT, LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150191760-A1 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | CELLSCRIPT LLC (US) | 2015-07-09 | — | — | US | disclosed |
| US-9005930-B2 | Kits and methods for generating 5′ capped RNA | CELLSCRIPT, LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140363876-A1 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | EPICENTRE TECHNOLOGIES | 2014-12-11 | — | — | US | disclosed |
| US-8846348-B2 | Kits and methods for generating 5′ capped RNA | CELLSCRIPT, LLC (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2010659-B1 | Kits and methods for generating 5' capped RNA | CELLSCRIPT INC (US) | 2014-06-18 | — | — | EP | disclosed |
| EP-2010659-A2 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | Epicentre Technologies (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20070281336-A1 | Kits and methods for generating 5' capped RNA | EPICENTRE TECHNOLOGIES (US) | 2007-12-06 | — | — | US | disclosed |
| WO-2007120863-A2 | KITS AND METHODS FOR GENERATING 5' CAPPED RNA | EPICENTRE TECHNOLOGIES (US) | 2007-10-25 | — | — | WO | disclosed |