Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614239 | 0.86 | KDM4E (0.60) | MEN1KMT2ARAB9AMTNR1AKDM4E | |
| SCHEMBL3667836 | 0.86 | MEN1 (0.52) | MEN1KMT2AMTNR1AMTNR1BNQO2 | |
| SCHEMBL29169605 | 0.81 | L3MBTL1 (0.58) | MEN1KMT2ARAB9AMTNR1AMTNR1B | |
| SCHEMBL9057781 | 0.80 | CNR1 (0.48) | MEN1KMT2ARAB9AKDM4ETP53 | |
| SCHEMBL1064566 | 0.79 | MTNR1A (0.58) | MEN1KMT2ARAB9AMTNR1AKDM4E | |
| SCHEMBL1064300 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL6450630 | 0.77 | MTNR1A (0.50) | MEN1KMT2ARAB9AMTNR1AMTNR1B | |
| SCHEMBL1067699 | 0.77 | MTNR1A (0.60) | MEN1KMT2AMTNR1A | |
| SCHEMBL1068332 | 0.77 | MTNR1A (0.60) | MEN1KMT2AMTNR1A | |
| SCHEMBL14550631 | 0.76 | KMT2A (0.53) | MEN1KMT2ARAB9AMTNR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258174-B2 | Method of inhibiting apoptosis | Somei, Masanori (JP) | 2012-09-04 | — | — | US | claimed |
| US-8258174-B2 | Method of inhibiting apoptosis | Somei, Masanori (JP) | 2012-09-04 | — | — | US | disclosed |