SCHEMBL1201856

SCHEMBL1201856

ON=C1CCCCC1c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
KDM4E B2RXH2 1/20 0.59
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42
GAA P10253 2/20 0.39
NOS1 P29475 2/20 0.39
NOS2 P35228 2/20 0.39
HPGD P15428 2/20 0.39
LMNA P02545 1/20 0.39
MCL1 Q07820 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 2/20 0.38
CHRNA7 P36544 1/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.35
KMO O15229 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1201854 1.00 ALDH1A1 (0.59) ALDH1A1KDM4EIGF1RALOX15GAA
SCHEMBL15874872 1.00 ALDH1A1 (0.59) ALDH1A1KDM4EIGF1RALOX15GAA
Water SCHEMBL8222140 0.98 ALDH1A1 (0.58) ALDH1A1KDM4EIGF1RALOX15GAA
SCHEMBL29497171 0.98 ALDH1A1 (0.58) ALDH1A1KDM4EIGF1RALOX15GAA
SCHEMBL29497128 0.98 ALDH1A1 (0.58) ALDH1A1KDM4EIGF1RALOX15GAA
SCHEMBL4608025 0.94 ALDH1A1 (0.53) ALDH1A1KDM4EIGF1RALOX15GAA
SCHEMBL4608020 0.94 ALDH1A1 (0.53) ALDH1A1KDM4EIGF1RALOX15GAA
Ether SCHEMBL8222137 0.88 ALDH1A1 (0.49) ALDH1A1KDM4EIGF1RALOX15GAA
SCHEMBL16392349 0.86 ALDH1A1 (0.44) ALDH1A1KDM4EIGF1RALOX15GAA
SCHEMBL7318404 0.78 ALDH1A1 (0.46) ALDH1A1KDM4ELMNAMAPTDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112830913-A Method for preparing 2, 5-furan diformylaldoxime 中国科学院宁波材料技术与工程研究所 2021-05-25 CN claimed
US-20070114155-A1 Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof TOTAL RAFFINAGE FRANCE (FR) 2007-05-24 US claimed
JP-2007501701-A 2007-02-01 JP claimed
EP-1660232-A1 HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF Total France (FR) 2006-05-31 EP claimed
WO-2005016518-A1 HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF TOTAL FRANCE (FR) 2005-02-24 WO claimed
US-5227028-A PROCESS FOR TREATING AMIDES DSM N.V. (NL) 1993-07-13 US claimed
CN-115872557-A Treatment method of caprolactam production wastewater 西安航天源动力工程有限公司 2023-03-31 CN disclosed
CN-112830913-A Method for preparing 2, 5-furan diformylaldoxime 中国科学院宁波材料技术与工程研究所 2021-05-25 CN disclosed
CN-108840824-A The preparation process of 4- phenyl cycloheptylamine 遵义医学院附属医院 2018-11-20 CN disclosed
WO-2014109712-A1 PALLADIUM-CATALYZED ASYMMETRIC (HETERO)ARYLATION AND VINYLATION OF KETONE ENOLATES TO PRODUCE TERTIARY STEREOCENTERS AT ALPHA(α)-POSITION NANAYNG TECHNOLOGICAL UNIVERSITY (SG) 2014-07-17 WO disclosed
US-8535515-B2 Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof TOTAL FRANCE (FR) 2013-09-17 US disclosed
EP-2307397-A1 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES Array Biopharma, Inc. (US) 2011-04-13 EP disclosed
US-7884243-B2 reacting 3,4-dihydo-1H-naphtalen-2-one oxime with acetic anhydride in tetrahydrofuran solvent using heterogenous catalyst ( Rh or Ir on Carbon support) in presence of hydrogen to perform hydrogenation/isomerization to form N-(3,4-Dihydro-naphthalen-2-yl)-acetamide ZACH SYSTEM (FR) 2011-02-08 US disclosed
EP-0464943-B1 Process for treating amides DSM NV (NL) 1995-03-22 EP disclosed
WO-1995000484-A1 N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 1995-01-05 WO disclosed
EP-0625145-A1 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS PFIZER INC. (US) 1994-11-23 EP disclosed
EP-0577203-A1 Process for the conversion of oximes into the corresponding amides DSM N.V. (NL) 1994-01-05 EP disclosed
WO-1993015059-A1 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS PFIZER INC. (US) 1993-08-05 WO disclosed
US-5227028-A PROCESS FOR TREATING AMIDES DSM N.V. (NL) 1993-07-13 US disclosed
EP-0464943-A1 Process for treating amides DSM N.V. (NL) 1992-01-08 EP disclosed