Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608020 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| SCHEMBL1201854 | 0.94 | ALDH1A1 (0.59) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| SCHEMBL1201856 | 0.94 | ALDH1A1 (0.59) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| SCHEMBL15874872 | 0.94 | ALDH1A1 (0.59) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| Water SCHEMBL8222140 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| SCHEMBL29497171 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| SCHEMBL29497128 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| SCHEMBL16392349 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| Ether SCHEMBL8222137 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EIGF1RALOX15L3MBTL1 | |
| SCHEMBL4607214 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431934-A | Method for synthesizing S-shaped amino compound | 陈永军 | 2017-02-22 | — | — | CN | claimed |
| CN-106431934-A | Method for synthesizing S-shaped amino compound | 陈永军 | 2017-02-22 | — | — | CN | disclosed |
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
| EP-1409452-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |
| WO-2002098846-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-12-12 | — | — | WO | disclosed |
| EP-1246797-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001042203-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |
| US-4350685-A | ASTHMA TREATMENT | SMITHKLINE CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | ALDH1A1 365/4885KDM4E 3086/4885IGF1R 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.