Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985228 | 0.89 | OPRD1 (0.65) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL1988467 | 0.89 | OPRD1 (0.65) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL12564507 | 0.89 | OPRD1 (0.65) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL12564520 | 0.89 | OPRD1 (0.65) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL12564541 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL1987098 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL1987818 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL12564583 | 0.89 | OPRD1 (0.69) | OPRD1OPRM1CYP1A2CYP3A4 | |
| SCHEMBL12564486 | 0.88 | OPRM1 (0.58) | OPRD1OPRM1 | |
| SCHEMBL12564479 | 0.88 | OPRM1 (0.58) | OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338889-B1 | Diazacyclic compounds having affinity for opioid receptors | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2012-08-29 | — | — | EP | disclosed |