⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689415 | 1.00 | — | — | |
| SCHEMBL15457829 | 1.00 | — | — | |
| SCHEMBL8341890 | 0.93 | DPP4 (0.40) | — | |
| SCHEMBL14161302 | 0.88 | — | — | |
| SCHEMBL16015160 | 0.80 | — | — | |
| SCHEMBL20781411 | 0.80 | — | — | |
| SCHEMBL1466543 | 0.80 | — | — | |
| SCHEMBL4687046 | 0.78 | DPP4 (0.42) | — | |
| SCHEMBL30978361 | 0.77 | DPP4 (0.45) | — | |
| SCHEMBL15360284 | 0.77 | NOS2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3003385-B1 | ANTIBODY COMPOSITION AND BUFFER SYSTEM THEREFOR | INNOVA BIOSCIENCES LTD (GB) | 2019-09-18 | — | — | EP | disclosed |
| US-9644005-B2 | Didemnin biosynthetic gene cluster in Tistrella mobilis | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2017-05-09 | — | — | US | disclosed |
| EP-2758519-B1 | DIDEMNIN BIOSYNTHETIC GENE CLUSTER IN TISTRELLA MOBILIS | UNIV KING ABDULLAH SCI & TECH (SA) | 2017-03-29 | — | — | EP | disclosed |
| EP-3020723-A1 | MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS | Enanta Pharmaceuticals, Inc. (US) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015191705-A1 | NON-CANONICAL INSULINS AND THEIR USES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-12-17 | — | — | WO | disclosed |
| US-20140296161-A1 | DIDEMNIN BIOSYNTHETIC GENE CLUSTER IN TISTRELLA MOBILIS | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2014-10-02 | — | — | US | disclosed |
| WO-2013163466-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. (US) | 2013-10-31 | — | — | WO | disclosed |
| EP-2491933-A1 | PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | Astellas Pharma Inc. (JP) | 2012-08-29 | — | — | EP | disclosed |