Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15457829 | 0.93 | — | — | |
| SCHEMBL12020146 | 0.93 | — | — | |
| SCHEMBL6689415 | 0.93 | — | — | |
| SCHEMBL14161302 | 0.86 | — | — | |
| SCHEMBL7140789 | 0.79 | DPP4 (0.38) | DPP4DPP8DPP9NOS2NOS3 | |
| SCHEMBL10349526 | 0.77 | DPP4 (0.50) | DPP4DPP8DPP9NOS2NOS3 | |
| SCHEMBL27978195 | 0.77 | DPP4 (0.50) | DPP4DPP8DPP9NOS2NOS3 | |
| SCHEMBL28319166 | 0.77 | DPP4 (0.50) | DPP4DPP8DPP9NOS2NOS3 | |
| Pipecolic Acid SCHEMBL22694374 | 0.76 | NOS2 (0.40) | DPP4DPP8DPP9NOS2NOS3 | |
| Pipecolic Acid SCHEMBL28398960 | 0.76 | NOS2 (0.40) | DPP4DPP8DPP9NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999010374-A1 | CYCLOSPORIN A CONJUGATES AND USES THEREFOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-03-04 | — | — | WO | disclosed |