Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 7/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12263491 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL17694087 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL16696033 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL13660356 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL7601472 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL16272140 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL14848659 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL12020855 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL70723 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 | |
| SCHEMBL13628955 | 1.00 | PRMT1 (0.68) | PRMT1BLMMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841134-B2 | Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications | BRUKER BIOSPIN CORPORATION (US) | 2014-09-23 | — | — | US | disclosed |
| US-8834846-B2 | Fluorescent NIRF activatable probes for disease detection | BRUKER BIOSPIN CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | BRUKER BIOSPIN CORPORATION | 2011-12-01 | — | — | US | disclosed |
| US-20090061532-A1 | FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION WITH NANOPARTICLES FOR IN VITRO AND IN VIVO APPLICATIONS | CARESTREAM HEALTH, INC. | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | CTSF, ENGASE, DNTT | PRMT1 2561/4885BLM 3701/4885MAPT 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.