SCHEMBL13628955

SCHEMBL13628955

CCCCCCCCCCCCN1/C(=C/C=C/C=C/C2=[N+](CCCCCCCCCCCC)c3ccccc3C2(C)C)C(C)(C)c2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 7/20 0.68
BLM P54132 2/20 0.58
MAPT P10636 2/20 0.58
MEN1 O00255 1/20 0.58
NPC1 O15118 1/20 0.58
USP2 O75604 1/20 0.58
S1PR2 O95136 1/20 0.58
LMNA P02545 1/20 0.58
POLB P06746 1/20 0.58
ALPG P10696 1/20 0.58
THRB P10828 1/20 0.58
PKM P14618 1/20 0.58
XBP1 P17861 1/20 0.58
CRHBP P24387 1/20 0.58
HTT P42858 1/20 0.58
RECQL P46063 1/20 0.58
RAB9A P51151 1/20 0.58
KMT2A Q03164 1/20 0.58
CRHR2 Q13324 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12263491 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL17694087 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL16696033 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL13660356 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL12020958 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL7601472 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL16272140 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL14848659 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL12020855 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1
SCHEMBL70723 1.00 PRMT1 (0.68) PRMT1BLMMAPTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090280064-A1 TRANSDERMAL DELIVERY OF OPTICAL, SPECT, MULTIMODAL, DRUG OR BIOLOGICAL CARGO LADEN NANOPARTICLE(S) IN SMALL ANIMALS OR HUMANS CARESTREAM HEALTH, INC. 2009-11-12 US disclosed
US-20090180964-A1 TRANSMUCOSAL DELIVERY OF OPTICAL, SPECT, MULTIMODAL,DRUG OR BIOLOGICAL CARGO LADEN NANOPARTICLE(S) IN SMALL ANIMALS OR HUMANS QUANTUM MEDICAL HOLDINGS, LLC 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090180964-A1 TRANSMUCOSAL DELIVERY OF OPTICAL, SPECT, MULTIMODAL,DRUG OR BIOLOGICAL CARGO LADEN NANOPARTICLE(S) IN SMALL ANIMALS OR HUMANS FABP2, PIGS, SLC35A1 PRMT1 4518/4885BLM 4139/4885MAPT 871/4885
US-20090280064-A1 TRANSDERMAL DELIVERY OF OPTICAL, SPECT, MULTIMODAL, DRUG OR BIOLOGICAL CARGO LADEN NANOPARTICLE(S) IN SMALL ANIMALS OR HUMANS PIGS, CUTA, CD68 PRMT1 4718/4885BLM 3469/4885MAPT 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.