SCHEMBL12021900

SCHEMBL12021900

C[C@@H](OC(=O)c1ccccc1C(=O)O)c1ccccc1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA4 P43681 1/20 0.43
HTR3A P46098 1/20 0.43
ALOX15 P16050 1/20 0.42
ALB P02768 1/20 0.41
GAA P10253 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
NOTUM Q6P988 1/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.38
ADRB2 P07550 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628211 1.00 ALDH1A1 (0.48) ALDH1A1CES2CES1CHRNB2CHRNB4
SCHEMBL3628328 1.00 ALDH1A1 (0.48) ALDH1A1CES2CES1CHRNB2CHRNB4
Alcohol SCHEMBL3628326 0.94 ALDH1A1 (0.50) ALDH1A1CES2CES1CHRNB2CHRNB4
Alcohol SCHEMBL3628209 0.94 ALDH1A1 (0.50) ALDH1A1CES2CES1CHRNB2CHRNB4
SCHEMBL12021827 0.81 ALDH1A1 (0.45) ALDH1A1ALOX15GAAHSD17B10TP53
SCHEMBL3631209 0.81 ALDH1A1 (0.45) ALDH1A1ALOX15GAAHSD17B10TP53
SCHEMBL3626019 0.81 ALDH1A1 (0.45) ALDH1A1ALOX15GAAHSD17B10TP53
Phthalic Acid SCHEMBL3628215 0.79 CES2 (0.54) ALDH1A1CES2CES1ALOX15ALB
SCHEMBL2996221 0.79 ALDH1A1 (0.57) ALDH1A1ALOX15HSD17B10TP53TSHR
Phthalic Acid SCHEMBL3628213 0.79 CES2 (0.54) ALDH1A1CES2CES1ALOX15ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1935866-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROBENZYL ALCOHOL CENTRAL GLASS CO LTD (JP) 2011-12-14 EP disclosed
EP-1935866-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROBENZYL ALCOHOL Central Glass Company, Limited (JP) 2008-06-25 EP disclosed