⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17678837 | 0.77 | GABRP (0.31) | — | |
| SCHEMBL21518266 | 0.77 | CA1 (0.36) | — | |
| SCHEMBL20485768 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL25812 | 0.77 | — | — | |
| SCHEMBL28213189 | 0.74 | — | — | |
| SCHEMBL27257823 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL28283558 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5363750 | 0.74 | — | — | |
| SCHEMBL6201194 | 0.74 | — | — | |
| SCHEMBL12913667 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725783-B1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-12-18 | — | — | EP | claimed |
| CN-116327950-A | Use of a composition for the treatment of neuropsychiatric symptoms of neurodegenerative diseases | 阿泽范药品公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116139282-A | Compositions and methods for treating neurodegenerative diseases | 阿泽范药品公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-106459021-B | Compositions and methods for treating neurodegenerative diseases | 阿泽范药品公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111295373-A | Compositions and methods for treating brain injury | 阿泽凡药物公司 | 2020-06-16 | — | — | CN | disclosed |
| US-20130131032-A1 | NEUROTHERAPEUTIC TREATMENT FOR SEXUAL DYSFUNCTION | REVAAX PHARMACEUTICALS, LLC (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2424498-A1 | CLAVULANATE FORMULATION FOR NEUROPROTECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS | Rexahn Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20110257147-A1 | NEUROTHERAPEUTIC TREATMENT FOR SEXUAL DYSFUNCTION | REVAAX PHARMACEUTICALS, LLC (US) | 2011-10-20 | — | — | US | disclosed |
| EP-1212055-B1 | Neurotherapeutic composition comprising a beta-lactam compound | REVAAX PHARMACEUTICALS LLC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2305251-A2 | Pharmaceutical compositions comprising clavulanic acid or derivative thereof for the treatment of sexual disorder | Revaax Pharmaceuticals LLC (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-0548186-A1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES. | BEECHAM GROUP PLC (GB) | 1993-06-30 | — | — | EP | disclosed |
| EP-0540606-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP plc (GB) | 1993-05-12 | — | — | EP | disclosed |
| EP-0521887-A1 | CEPHALOSPORINS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Beecham Group p.l.c. (GB) | 1993-01-13 | — | — | EP | disclosed |
| EP-0504216-A1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Beecham Group p.l.c. (GB) | 1992-09-23 | — | — | EP | disclosed |
| WO-1992004353-A1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES | BEECHAM GROUP PLC (GB) | 1992-03-19 | — | — | WO | disclosed |
| WO-1991014692-A1 | CEPHALOSPORINS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0416814-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1991-03-13 | — | — | EP | disclosed |
| EP-0416810-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | Beecham Group p.l.c. (GB) | 1991-03-13 | — | — | EP | disclosed |
| EP-0308559-A2 | Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1989-03-29 | — | — | EP | disclosed |
| EP-0219926-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-04-29 | — | — | EP | disclosed |