Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 2/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237673 | 0.86 | SLC7A5 (0.53) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL12337990 | 0.83 | SLC7A5 (0.59) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL29589017 | 0.78 | CES2 (0.54) | KDM4ETDP1HTR2APTGS2RECQL | |
| SCHEMBL8234613 | 0.77 | SLC7A5 (0.51) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL13703211 | 0.77 | SLC7A5 (0.51) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL2779653 | 0.75 | SLC7A5 (0.61) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL6771201 | 0.75 | SLC7A5 (0.61) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL2779651 | 0.75 | SLC7A5 (0.61) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL13515476 | 0.74 | LTA4H (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1993787 | 0.74 | SLC7A5 (0.59) | TPH1SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399893-A2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | Ambrx, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |