Sugi Predict

Sugi Predict / Compounds / SCHEMBL120295

SCHEMBL120295

SCHEMBL120295

BrCc1cccc(-c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.59
▸ TRPA1 O75762 1/20 0.59
▸ TSHR P16473 1/20 0.59
▸ AGXT P21549 1/20 0.55
▸ CYP4F2 P78329 1/20 0.46
▸ CYP4A11 Q02928 1/20 0.46
▸ AOC3 Q16853 3/20 0.46
▸ GGPS1 O95749 2/20 0.44
▸ MAOA P21397 2/20 0.44
▸ TAAR1 Q96RJ0 1/20 0.44
▸ HRH3 Q9Y5N1 1/20 0.44
▸ CYP11B1 P15538 1/20 0.44
▸ CYP11B2 P19099 1/20 0.44
▸ CYP19A1 P11511 1/20 0.44
▸ PRKCI P41743 1/20 0.44
▸ BCL2 P10415 1/20 0.43
▸ PTGES O14684 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ KDM1A O60341 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3357853 0.98 TRPA1 (0.56) ALDH1A1TRPA1TSHRAGXTCYP4F2
SCHEMBL16675041 0.96 TRPA1 (0.54) ALDH1A1TRPA1TSHRAGXTCYP4F2
SCHEMBL16675050 0.96 TRPA1 (0.54) ALDH1A1TRPA1TSHRAGXTCYP4F2
Formaldehyde SCHEMBL27622040 0.94 TRPA1 (0.52) ALDH1A1TRPA1TSHRAGXTCYP4F2
SCHEMBL9707122 0.94 TSHR (0.58) ALDH1A1TRPA1TSHRAGXTCYP4F2
SCHEMBL1259618 0.93 TRPA1 (0.52) ALDH1A1TRPA1TSHRAGXTCYP4F2
SCHEMBL30987236 0.93 TRPA1 (0.52) ALDH1A1TRPA1TSHRAGXTCYP4F2
SCHEMBL30987239 0.88 TRPA1 (0.50) ALDH1A1TRPA1TSHRAGXTCYP4F2
SCHEMBL1311054 0.88 TRPA1 (0.50) ALDH1A1TRPA1TSHRAGXTCYP4F2
Biphenyl SCHEMBL7524026 0.85 TSHR (0.82) ALDH1A1TRPA1TSHRAGXTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622595-A Novel preparation method of azilsartan medoxomil sylvite and its intermediate CHONGQING LAND TOWER PHARMACEUTICAL CO LTD 2016-06-01 — — CN claimed
US-20260124201-A1 CYCLOPENTANE COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (JP) 2026-05-07 — — US disclosed
US-12503475-B2 Bicyclic-heterocycle derivatives and their uses as orexin-2 receptor agonists CENTESSA PHARMACEUTICALS (UK) LIMITED (GB) 2025-12-23 — — US disclosed
EP-4600242-A1 CYCLOPENTANE COMPOUND Kissei Pharmaceutical Co., Ltd. (JP) 2025-08-13 — — EP disclosed
US-20250179017-A1 CARBOXAMIDE COMPOUNDS AS PGE2 RECEPTOR ANTAGONISTS GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) 2025-06-05 — — US disclosed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 — — US disclosed
CN-119968355-A Cyclopentane compounds 橘生药品工业株式会社 2025-05-09 — — CN disclosed
US-20250100968-A1 BICYCLIC-HETEROCYCLE DERIVATIVES AND RELATED USES OXFORD FINANCE LLC 2025-03-27 — — US disclosed
EP-4486445-A1 BICYCLIC-HETEROCYCLE DERIVATIVES AND RELATED USES Centessa Pharmaceuticals (UK) Limited (GB) 2025-01-08 — — EP disclosed
EP-4482824-A1 CARBOXAMIDE COMPOUNDS AS PGE2 RECEPTOR ANTAGONISTS Guangdong Newopp Biopharmaceuticals Co., Ltd. (CN) 2025-01-01 — — EP disclosed
US-4329518-A INSECTICIDES, ACARICIDES, MITICIDES FMC CORPORATION (US) 1982-05-11 — — US disclosed
EP-0049977-A1 Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them FMC Corporation (US) 1982-04-21 — — EP disclosed
EP-0020685-A4 INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. FMC CORP (US) 1981-07-16 — — EP disclosed
EP-0001712-B1 (1,1'-BIPHENYL)-3-YLMETHYL 3-(2,2-DIHALOETHENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATES, AGRICULTURAL COMPOSITIONS AND METHODS OF USE AND MANUFACTURE FMC Corporation (US) 1981-04-15 — — EP disclosed
EP-0020685-A1 INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. FMC CORP (US) 1981-01-07 — — EP disclosed
US-4238505-A HIGH TOXICITY FMC CORPORATION (US) 1980-12-09 — — US disclosed
US-4214004-A MITICIDES FMC CORPORATION (US) 1980-07-22 — — US disclosed
WO-1980001163-A1 INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS FMC CORP (US) 1980-06-12 — — WO disclosed
EP-0001712-A2 (1,1'-Biphenyl)-3-ylmethyl 3-(2,2-dihaloethenyl)-2,2-dimethylcyclopropanecarboxylates, agricultural compositions and methods of use and manufacture FMC Corporation (US) 1979-05-02 — — EP disclosed
US-4130657-A INSECTICIDE, MITICIDE FMC CORPORATION (US) 1978-12-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503475-B2 Bicyclic-heterocycle derivatives and their uses as orexin-2 receptor agonists HCRTR2, HCRTR1, CRHR2 ALDH1A1 3291/4885TRPA1 1171/4885TSHR 244/4885
US-20250179017-A1 CARBOXAMIDE COMPOUNDS AS PGE2 RECEPTOR ANTAGONISTS PTGER1, PTGER2, CNR2 ALDH1A1 940/4885TRPA1 111/4885TSHR 489/4885
US-20250100968-A1 BICYCLIC-HETEROCYCLE DERIVATIVES AND RELATED USES HCRTR2, HCRTR1, CRHR1 ALDH1A1 2902/4885TRPA1 1674/4885TSHR 534/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 ALDH1A1 800/4885TRPA1 3164/4885TSHR 1283/4885
US-20260124201-A1 CYCLOPENTANE COMPOUND HCRTR1, HCRTR2, CNR1 ALDH1A1 1144/4885TRPA1 1046/4885TSHR 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.