Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.61 |
| ▸ | TUBB | P07437 | 4/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.61 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.61 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.61 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.61 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.61 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.61 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.61 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.61 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.61 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092523 | 0.82 | TUBB4A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8736425 | 0.82 | AR (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14586634 | 0.80 | AR (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7252472 | 0.78 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19296418 | 0.78 | TUBB1 (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12260863 | 0.78 | TUBB1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19296413 | 0.78 | ALDH1A1 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12748396 | 0.78 | TEAD4 (0.64) | ARACHEALDH1A1MAPTHTT | |
| SCHEMBL5583756 | 0.77 | ALDH1A1 (0.63) | ARACHEALDH1A1MAPTHTT | |
| SCHEMBL19853644 | 0.77 | AR (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399584-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |