Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | UBE2N | P61088 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | HTR6 | P50406 | 8/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3615171 | 0.84 | HTR6 (0.78) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL22339784 | 0.84 | KDM4E (0.66) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL29414758 | 0.82 | KDM4E (0.68) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL3615167 | 0.82 | KDM4E (0.68) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL28018212 | 0.82 | KDM4E (0.68) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL29460860 | 0.82 | KDM4E (0.68) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL5429439 | 0.82 | KDM4E (0.68) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL517434 | 0.82 | KDM4E (0.68) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL949348 | 0.81 | LMNA (0.82) | KDM4EUBE2NL3MBTL1HTR6ALOX5 | |
| SCHEMBL29694480 | 0.81 | KDM4E (1.00) | KDM4EUBE2NL3MBTL1HTR6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110027817-A1 | TAU PROTEIN SCREENING ASSAY | ARANCIO OTTAVIO | 2011-02-03 | — | — | US | disclosed |
| WO-2009033151-A1 | TAU PROTEIN SCREENING ASSAY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-03-12 | — | — | WO | disclosed |