SCHEMBL12034643

SCHEMBL12034643

Cc1cc(O)cc(N2C(=O)c3ccc(-c4ccc5c(c4)C(=O)N(C)C5=O)cc3C2=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.46
ESR2 Q92731 3/20 0.46
APP P05067 2/20 0.43
ALDH1A1 P00352 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
CA9 Q16790 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
GRM5 P41594 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ANPEP P15144 1/20 0.40
DPP4 P27487 1/20 0.40
POLB P06746 1/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12034645 0.85 CA9 (0.48) ESR1ESR2APPALDH1A1TSHR
SCHEMBL12163404 0.83 CA9 (0.54) ALDH1A1HSD17B10CA9CA12CA1
SCHEMBL7591247 0.82 ALDH1A1 (0.61) ESR1ESR2APPALDH1A1NPC1
SCHEMBL13533870 0.81 ALDH1A1 (0.59) ESR1ESR2APPALDH1A1NPC1
SCHEMBL13018342 0.81 ALDH1A1 (0.59) ESR1ESR2APPALDH1A1NPC1
SCHEMBL7334559 0.81 GRM5 (0.58) ESR1ESR2NPC1RAB9AGRM5
SCHEMBL2603489 0.80 MEN1 (0.48) ALDH1A1NPC1RAB9AHSD17B10TSHR
SCHEMBL12034649 0.80 MAPK1 (0.56) ESR1APPALDH1A1NPC1RAB9A
SCHEMBL10053401 0.76 ALDH1A1 (0.59) APPALDH1A1HSD17B10TSHRKDM4E
SCHEMBL7594849 0.75 MEN1 (0.54) ESR1APPALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110311871-A1 NEGATIVE ELECTRODE FOR LITHIUM SECONDARY BATTERIES AND LITHIUM SECONDARY BATTERY SANYO ELECTRIC CO., LTD. (JP) 2011-12-22 US disclosed