Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792888 | 0.87 | GRM5 (0.62) | GRM5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5604859 | 0.87 | GRM5 (0.62) | GRM5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7386922 | 0.81 | GRM5 (0.56) | GRM5MEN1KMT2A | |
| SCHEMBL12034643 | 0.81 | ESR1 (0.46) | GRM5MEN1KMT2AESR1NPC1 | |
| SCHEMBL20437115 | 0.79 | LMNA (0.44) | GRM5ESR1NPC1RAB9AESR2 | |
| SCHEMBL12034645 | 0.77 | CA9 (0.48) | ESR1ESR2 | |
| SCHEMBL1662738 | 0.77 | ESR1 (0.80) | GRM5MEN1KMT2AESR1NR1H3 | |
| SCHEMBL30758580 | 0.77 | MEN1 (0.67) | MEN1KMT2ANR1H3SCN2A | |
| SCHEMBL30777591 | 0.77 | MEN1 (0.67) | MEN1KMT2ANR1H3SCN2A | |
| SCHEMBL259386 | 0.77 | MEN1 (0.67) | MEN1KMT2ANR1H3SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778839-B1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| US-5824679-A | Phosphanoxides--preparation and use | BOEHRINGER MANNHEIM GMBH (DE) | 1998-10-20 | — | — | US | disclosed |
| US-5795892-A | ANTICOAGULANTS | BOEHRINGER MANNEIM GMBH (DE) | 1998-08-18 | — | — | US | disclosed |
| EP-0778829-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006832-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |