Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16674651 | 0.91 | CPB1 (0.55) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL12035506 | 0.88 | ALDH1A1 (0.64) | CPB1ALDH1A1GAATSHREPHX1 | |
| SCHEMBL28703957 | 0.86 | CPB1 (0.55) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL16674650 | 0.86 | CPB1 (0.55) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL714522 | 0.86 | CPB1 (0.53) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL714949 | 0.86 | CPB1 (0.53) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL715808 | 0.86 | CPB1 (0.53) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL716516 | 0.86 | CPB1 (0.53) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL713199 | 0.86 | CPB1 (0.53) | CPB1ALDH1A1GAATSHRMAPT | |
| SCHEMBL16674649 | 0.85 | CPB1 (0.56) | CPB1ALDH1A1GAATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110312990-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20110077266-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077266-A1 | Diamine Derivatives | F2, TFPI, F3 | CPB1 136/4885ALDH1A1 793/4885GAA 2113/4885 |
| US-20110312990-A1 | Diamine Derivatives | C9, C1S, C1R | CPB1 3433/4885ALDH1A1 3734/4885GAA 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.